cours proposé en 2015
Module M1 Génotype-Phénotype (30h) -V. Courtier-Orgogozo
Ce module est proposé aux étudiants de l’ENS de Paris.
Cours (cliquez sur les liens pour obtenir les PDFs)
Introduction on genetics and the genotype-phenotype map
Mapping the genes underlying phenotypic changes of interest
Interactions between several loci, Epistasis, Super Genes, Pleiotropy, Interactions Genes x Environment
Genetic Screens, CRISPR and gene drive
Quantitative Genetics, Noise, Cryptic Variation, Robustness, Epigenetics
Meta-analysis of the Genes underlying Phenotypic Changes
Genetic bases of phenotypic plasticity (Jean-Michel Gibert)
The Genotype-Phenotype Map for Shape: Insights from Morphogenesis (Alexis Matamoro-Vidal)
Coloration: a great system to study genotype-phenotype relationships (Thibault Lorin)
Petits exercices de génétique (3-4h, en anglais)
TD “Evolution of coat color in snowshoe hares”
TD “Evolution of polyphenism in the Lepidoptera Manduca sexta”
Exercice transition/transversion en utilisant les données de Gephebase
Gephebase practicals presentation
Protocol
Gephebase-entries
ExtractedData
Full Google Drive folder